Sep 03, · The use of a peripheral nerve stimulator is recommended in assessing the degree of muscular relaxation with all neuromuscular blocking drugs. The ED90 (dose required to produce 90% suppression of the muscle twitch response with balanced anesthesia) has averaged mg/kg ( to mg/kg in various studies). Jan 04, · Usual Adult Dose for Pathological Hypersecretory Conditions. Oral: 40 mg orally 2 times a day-Maximum dose: mg/day Parenteral: Initial dose: 80 mg via IV infusion every 12 hours, given over at least 2 minutes OR over 15 minutes-Maintenance dose: 80 mg via IV infusion every 8 to 12 hours, given over at least 2 minutes OR over 15 minutes.
Aug 18, · Use adult dosing. 1 to 10 years: May require a slightly higher initial dose than adults and may also require supplementation slightly more often than adults. Infants under 1 year of age but older than 7 weeks: Are moderately more sensitive to this drug on a mg/kg basis than adults and take about times as long to recover. Dose should be calculated based on ideal body weight. Injection. Load: mg/kg IVP over 60 sec OR ; mg/kg IVP if following succinylcholine, PLUS; Maintenance: mg/kg .
Sep 16, · Usual Adult Dose for Anesthesia. TRACHEAL INTUBATION: Initial dose: mg/kg IV. -An 80% block or greater is attained in a time of 1 ( to 6) minute (s) and most patients have intubation completed within 2 minutes. -Maximum blockade is achieved in most patients in less than 3 minutes. The dose required to produce 90% suppression of the muscle twitch response (ED90) averages 57 mcg/kg (range 49—62 mcg/kg) under balanced anesthesia. After administration, the drug is rapidly distributed to the extracellular space and is rapidly extracted by the liver.
Oct 12, · Data currently insufficient for specific dosage recommendations. 1 Some clinicians suggest usual initial dose; others suggest a reduced initial dose. Adjust maintenance dosing (probably with reduced doses) carefully according to patient’s response. (See Hepatic Impairment under Cautions.). dose of Norcuron under nitrous oxide in oxygen anaesthesia was found to be approximately the same (approx. 47 µg/kg body weight) as in adults. The onset of time is considerably shorter in infants as compared to children and adults, probably due to the shorter circulation time and relatively large cardiacoutput. Also, greater sensitivity of the.